A computer recently was infected by the Palladium virus twice. The first time Malware bytes anti-malware and Windows Defender claimed to have it fixed. However after checking the log files I looked in C:\documents and settings\networkservice\application data I discovered that there were a lot of left over files that had the infection. It creates random files of its infection so it can reinfect the computer. You need to manually remove these files.
In the picture I put a box around the files left over after the infection.